several of us [at Science-Based Medicine] consider EBM to be incomplete in its gathering of evidenceHe also observes
that human RCTs, as good as they are at minimizing bias or chance deviations from population parameters, cannot ever be expected to provide, by themselves, objective measures of truth. There is still ample room for erroneous conclusions. Without using broader knowledge (science) to guide our thinking, we will plunge headlong into a thicket of errors—exactly as happened in parapsychology for decades and is now being repeated by its offspring, “CAM” research.In his view EBM, at present, is a "subset of Science-Based Medicine (SBM), because EBM by itself is incomplete." When it incorporates all the evidence EBM and SBM will be "interchangeable."
Update: Evidence in Medicine discusses EBM and its limitations too.